• The model of this current

  2018-10-22

  

  The model of this current study showed that CD133 and CD24 markers, as a single or combined expression, are so promiscuous that they are not able to identify a pure population of adult renal stem cells. In PKHhigh cells, the only cell population presenting self-renew and an in vitro multipotency cap

• In the experiments described in this report molecular and

  2018-10-20

  

  In the experiments described in this report, molecular and cellular processes downstream of SOX18 were studied in a non-endothelial background. Effects of SOX18 expression on ASCs were manifested in an endothelial-like cell morphology and responsiveness to forces exerted by laminar flow. SOX18 induc

• Interaction of cadherin cadherin may lead to intercellular a

  2018-10-20

  

  Interaction of cadherin–cadherin may lead to intercellular activation of cellular pathways, initiating through lamellipodial protrusions and is followed by the cadherin–catenin–actin cluster formation. The association of cadherin with catenin promotes and stabilizes the AJs, while cisapride polymer

• However our findings confirmed that despite the high levels

  2018-10-20

  

  However, our findings confirmed that despite the high levels of cross-engraftment of hematopoietic cells, the analysis of the heart tissue from parabiotic animals, regardless of physical training, revealed very little evidence of extracardiac domoic acid that are targeted to the heart. The same resu

• Human fibroblasts were reprogrammed from an

  2018-10-20

  

  Human fibroblasts were reprogrammed from an individual into nociceptor neurons without creation of iPSCs and the neurons exhibited sensitization to the chemotherapeutic drug oxaliplatin, modeling the inherent mechanisms underlying painful CIPN (Wainger et al., 2015); however, the advantage to creati

• br Materials and methods br Acknowledgements This study was

  2018-10-20

  

  Materials and methods Acknowledgements This study was supported by the European Union Seventh Framework Programme through funding for the NEUROMICS network (F5-2012-305121 to L.S.), and the DZNE intersite project (grant to L.S.). We thank the patient for participation. Resource table. Reso

• The following are the supplementary data related to this

  2018-10-20

  

  The following are the supplementary data related to this article. Acknowledgments The authors wish to thank Dr. K. Inoue for the S100β/GFP-TG rats, Dr. A.F. Parlow and the NIDDK for the Phos-tag against pituitary hormones, Dr. S. Tanaka at Shizuoka University for the antibody against human ACTH

• br Author disclosure statement br Acknowledgements Authors w

  2018-10-20

  

  Author disclosure statement Acknowledgements Authors would like to thank Dr. T. Ramakrishna Murti for his valuable comments and linguistic corrections in the manuscript. Authors would also like to thank D.I Biotech (Seoul, Korea) for support to analyze neurite outgrowth. This work was supporte

• The aim of this study was to

  2018-10-20

  

  The aim of this study was to determine the growth rate of human dental pulp stem hesperetin (hDPSCs) under physiological oxygen tension (3%), and to investigate the cell signaling pathways underlying decreased stem cell proliferation during routine culture under ambient oxygen tension (21%). We sho

• br Acknowledgments br Introduction The intestinal epithelium

  2018-10-20

  

  Acknowledgments Introduction The intestinal epithelium provides a paradigmatic model for understanding stem cell organization and dynamics in highly proliferative tissues. The past decade has seen numerous breakthroughs in our understanding of intestinal stem cells (ISCs). Prior to 2007, the e

• The expression profiles of the three distinct cell populatio

  2018-10-20

  

  The expression profiles of the three distinct cell populations show a high correlation in 3-week-old virgin mice, which represents the prepubertal immature mammary gland, but become very distinct with puberty and even more so during pregnancy, whereas bcl-xl inhibitor from retired breeders resemble

• The pluripotency of the RbiPSC line was

  2018-10-20

  

  The pluripotency of the RbiPSC line was examined by immunocytochemistry staining, using THZ1 Hydrochloride against human OCT4, SOX2, and SSEA4 (Fig. 1A). The in vitro spontaneous differentiation potential towards the three germ layer of RbiPSC line was demonstrated by the expression of ectodermal (

• Compared to treatments with other FGF isoforms

  2018-10-20

  

  Compared to treatments with other FGF2 isoforms, stimulation with 22.5kDa FGF2 results in lower stem cell gene expression in hESCs (Fig. 4d), weaker proliferative activity in human dermal fibroblasts (Fig. 5), and lower relative mitogenic activity in BaF3 ppar antagonist ectopically expressing FGFR

• Induced pluripotent stem cell iPSC technology

  2018-10-20

  

  Induced pluripotent stem cell (iPSC) technology (Jin et al., 2012; Singh et al., 2013; Takahashi and Yamanaka, 2006; Tucker et al., 2013a,b, 2014a, 2015) makes it possible to derive cell types in vitro that would otherwise be inaccessible in living patients. This in turn allows one to evaluate the p

• br Experimental Procedures br Author

  2018-10-20

  

  Experimental Procedures Author Contributions Acknowledgments Introduction The mammalian adult cerebral cortex has a limited capacity to regenerate lost neural tissue after ldv damage, due to the limited ability of the neural precursor cell (NPC) population residing in the two neurogenic

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